EFFECT OF HYPERVITAMINOSIS "0" ON THE OVARIES OF THE ADULT ALBINO RAT

Document Type : Original Article

Authors

Anatomy Department, Faculty of Medicine, Cairo University

Abstract

Although vitamin "D" is typically classified as a fat soluble vitamin its active form in the body acts as a hormone (James and Otto, 1975). The importance of vitamin "0" in calcium and phosphorus metabolism was previously explained by many research workers. Braidman and Anderson (1985) stated that in addition to the known target organs for vitamin "0",
specific receptors for vitamin D (VDRs) were detected in a number of other tissues, namely: skin, pancreas, lymphocytes and reproductive organs as the testis, ovary and uterus suggesting a wider spectrum of vitamin "D" biological
effects. Many observations indicated that vitamin "D" plays an important role in the female reproductive system. Kumar et at, (1979) found that the circulating level of vitamin "D" was raised at the time of ovulation and during pregnancy and diminished in the postmenopausal state. 

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