TOXIC AND TERATqGEI{IC EFFECTS OF SOME DRUGS ON CHICK nnfnnYO

Document Type : Original Article

Author

Department ol Zoology, Faeultg ol Science, Ain Shams Uniuersity, EgUpt

Abstract

The toxicity and teratogenicity of three commonly used drugs were fested in <Douky 4l chick embryos.
Avil ( 1 - pheny ? - pyridyl - B - dimethyl aminopropane) is an anti. histaminic and antiallergic drug, Nesdonal (a derivative of the acid 2 - ethyl - 5 methyl - 1 -butyl - 5 thiobarbitone) is a general anaesthetic drug, while Revrin ( pyrrolidino. methyl tetracycline) is a common antibiotic.
Antihistaminie drugs are generally thought to be safe, Meclozine for instance has been thouroughly investigated and several independent studies in difierent parts of the world failed to demonstrate any deleterious efiect on the embryo or fcetus (Wollam, f966). 

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